Signals Research Suite Connect
- Connect++
- 1 February 7th at 8AM PST | 11AM EST | 5PM CET
Harnessing the Power of Antibody Drug Conjugates: How the Signals Research Suite Advances Multi-Modal Drug Development
The Signals™ Research Suite is the first integrated informatics platform purpose-built to accelerate multi-modal drug development like ADCs and is composed of a trio of scientific software applications:
1. Signals™ Notebook: The premier cloud-based electronic lab notebook that facilitates creation and communication about molecules of interest via hierarchical editing language for macromolecules (HELM), powered Chemdraw®.
2. Signals™ VitroVivo: For data analysis, visualization, and curve fitting bioassay results for standardized and consistent results, powered by Spotfire®.
3. Signals™ Inventa: Enabling multi-assay or multi-study comparison, powered by Spotfire, with the ability to find the best candidate to move forward, accelerating decision making. Researchers gain better visibility into ADC candidate profiling and can quickly determine structure-activity and structure- property relationships across modalities to select optimal conjugation sites and pairings.
Attendees will gain insights into the latest trends and challenges in ADC development, informed by recent research and advancements in the field. The presentation will also emphasize the importance of integrating various data types and sources in the ADC development process, showcasing how the Signals Research Suite facilitates this integration, thereby driving more efficient, safer drug development.
In this webinar, we will demonstrate how the Suite supports key ADC workflows, including:
- IgG sequence analysis, CDR grafting, and humanization
- Conjugation site mapping and payload attachment chemistry
- ADC stability, potency, and selectivity testing
- Pharmacokinetic and efficacy studies in vivo