Signals One™ - What's New
Signals One™ is a complete, integrated data capture, processing & analysis SaaS software for scientific research. Capture, manage, and share experiment data, notes and research findings in a secure and accessible environment built on the foundation of the Signals Platform.
Check out the latest improvements:
Releases By Year
What's New
We are delighted to release our new version of Signals, 26.1. This release brings enhancements in Tasks, Materials, Data Analytics, Inventory and Tables amongst others. We have new beta capabilities around Ontologies, inherited Material properties and improving the display of tables. The beta capabilities around Contextual Lists are now available to all systems. Finally, we have also fixed a number of small bugs.
The following improvements are available for users, administrators and developers on the Signals platform. Certain features may only be available with appropriate licensing and/or with enablement by an administrator.
- Fundamentals
– Ontologies integration allows terms to be used across experiments, materials, tables, and more (beta) - Data Workflows & Analytics*
– Spotfire-based workflows now integrate the Publish Results to Data Factory app
– Data Assembly download - SAR & Decisioning*
– Bulk Delete published data via the Inventa Dashboard - Chemistry
– HELM editor now supports monomer structure search
– LogP calculation now available in the Analysis panel
– Drag-and-drop of SD/RD files onto the ChemDraw canvas converts to CDXML
– Generate hairpins from oligonucleotides using the auto-pair tool
– Allowing for edits to the Material ID in the Stoich grid
– Updates to Salt Stripping to allow for fractional salts - Tables
– Contextual Lists available to all systems *
– Internal Reference type properties can be used as source for Contextual Lists available to all systems *
– Hidden columns in Tables can be temporarily unhidden
– Calculate Minimum
– Updated admin experience for Admin Defined Tables and Variation Tables (beta)
– Conditional data entry for Number properties in Admin Defined Tables and Variation Tables (beta) - Worksheets
– Contextual List property available to all systems * - Inventory
– Display barcode on Location and Container cards in inventory
– Allow admins to define autofill patterns for grid locations
– Support bulk export of internal requests - Materials
– Type in sequence registration in Materials Library
– Lineage viewer Show/Hide Properties UI update
– Inherited Properties for Materials (beta) - Tasks and Requests
– Updates to the Task Modal to facilitate different modes of task creation - Administration
– Configuration Transfer of Contextual Lists available to all systems
– Configuration Transfer of Contextual Lists in Worksheets available to all systems - Integrations & APIs
– New API to fetch Signals Version
– New APIs to support Hierarchical Tables
– Enhanced API to allow adding Assets to materials table
– New CRO APIs for file attachment and chemical compliance
– Enhanced APIs for bulk updating Containers
* Requires Signals One license
† Requires Signals Synergy license
We also fixed several small bugs in this release. Details of the enhancements are described below.
Data Factory Administrators should note that the syncing material library may now be changed after deleting any Data Factory projects.
Data Factory Administrators should note that legacy Data Factory projects will be fully deprecated in a future release. A straightforward migration path will be provided in an upcoming release to support this transition.
Data Factory administrators should be aware that the behavior of System Generated IDs will be updated in a future release. File-based publications will no longer support System Generated IDs.
Data Factory administrators should also note that the Advanced Security policies in Inventa apply an "AND" logic across all user groups, restricting access if any groups lack permissions. This behavior differs from the standard Signals security model and will be fixed to align with the standard in a future release.
Administrators should be aware that we will be retiring the CRAIS Checker capability from Signals Notebook and Signals One. This capability, which was only available via request, was built to allow integration specifically to the Patcore CRAIS Checker database. Such workflows have been superseded by the Chemical "External Checking" capability which can be used against any chemical compliance database. Any customers still using the CRAIS checker are encouraged to update their workflows to use this capability instead. We encourage any customers who require assistance with this transition to contact our support organization and/or engage with our Professional Services team. The CRAIS Checker capability will be retired by March 31st 2026.
Administrators are recommended to subscribe to the channels within our support news site found at https://support.revvitysignals.com/hc/en-us/categories/360004446171-Support-News which contains more information about releases and other pertinent product information.
This content is anticipated for release on our Production E3 environments, and for Private Cloud customers on our deferred release schedule, in July 2026.
Further Details
The following improvements are available for users, administrators and developers on the Signals platform. Certain features may only be available with appropriate licensing and/or with enablement by an administrator.
Data Workflows & Analytics
The new app allowing to publish analysis results, associated to mandatory Compound/Batches pairs, to Data Factory 2.0 is now integrated in the out of the box workflows.
The Data Assembly step of the In Vitro Analysis allows assembling the data from the instrument with multiple sources like plate format information and external lookup tables. It is now possible to download, with the click of a button, the full content of the resulting table.
SAR & Decisioning
Users can now bulk delete published data via the Inventa Dashboard. After uploading a file that contains a list of Unique Result IDs, users can choose “Bulk Delete” to permanently delete those records from Data Factory. Note: System Generated URIs must be disabled by an Administrator in order to use Bulk Delete.
Chemistry
The HELM editor now supports structure-based monomer search alongside text search, using a new 'Structure' button and preview panel in the Peptide, RNA/DNA, and Chem/Blob tabs. Structures can be pasted from common formats (cdxml, cdx, SMILES, molV2000/3000, InChI) and searched as substructure, similar, full, exact, or full including tautomers, with results returned directly in the monomer panel. Structure and text filters can be combined to refine monomer results within the active library.
LogP is now available as a calculated property in the analysis panel of the ChemDraw editor. The calculation is based on the current selection and supports structures containing fewer than 1,000 atoms or 150 heavy atoms.
SD and RD files can now be dragged and dropped onto a ChemDraw canvas and converted automatically to cdxml for continued editing.
The ‘auto-pair’ tool in the ChemDraw editor can now generate hairpins from a single oligonucleotide sequence. It identifies the region of maximum complementarity within the strand, places hydrogen bonds between complementary nucleobases, and forms a hairpin loop from the remaining unpaired nucleobases.
Users will now be able to unlink the Material ID of chemicals added via the Quick Add. Unlinking the material does not erase the chemical from the drawing. It just removes the Material ID which previously could not be removed or altered.
In an update to the behavior of the Salt Stripper for Normalized Compounds, partial salts will now be fully stripped where previously only whole salt coefficients were recognized. This will not alter the batch level chemical name, MF, or mass values as those are calculated from the unaltered batch structure. This will just allow the salt table to more accurately reflect the stripped salts
Tables
Contextual Lists are now available to systems with a Signals One license.
End users can now temporarily display hidden columns in relevant Tables even if they do not have Edit on the content the Table is in. The Cog icon will now be shown and will display in blue if hidden columns contain data. The hidden columns can be exposed from this menu. The display of the columns is transient and the table will be returned to its original state upon a page refresh. This applies to all relevant tables including Admin Defined Tables, Variation Tables, Hierarchical Tables, Design Tables, Sample Tables and Material Tables.
A Configuration Administrator can also define equations to calculate the minimum of a series of data. The functions MIN and MINOVER allow the selection of the lowest number of a set of data. If applied in a Header, the conditional minimum can be calculated using MINOVER or by nesting an IF functions within MIN.
Worksheets
Contextual List properties into Worksheets is now available to all systems with a Signals One license.
Inventory
Barcodes are now visible on both the Location and Container Card as well as in the List view within Inventory. The display order of barcodes follows the property sequence defined in Location Type and Container Type settings.
Admin users can now define grid autofill behaviour by setting up pattern mappings for Location Types. Available options include User Selection, Left-to-Right Pattern or Top-to-Bottom Pattern.
This enhancement ensures grid locations are populated according to the pattern selection configured in the Location Type settings.
Inventory users with Export Container permissions can now export Internal Requests in two formats, No Structure (CSV) or SDF.
This enhancement allows users to download and share data in the required structure for further processing or integration with other systems.
Materials
End users can now register sequence-based materials such as DNA, RNA, and Proteins and the pre-configured Plasmids library by copying in a sequence from their clipboard. A sequence string, FASTA, GenBank, and GenPept entries can be pasted in when registering materials in the smart folder.
The material lineage table Show/Hide Properties menu has been updated to more concisely display properties from various material libraries present in the viewer. Material library names now act as a header when scrolling through the list of selectable properties.
Tasks and Requests
The Task creation modal has been updated to more clearly indicate the number of tasks that will be created and allow for a single task to include all references from the Sample Bulk actions as seen below.
The Task creation modal driven from the “Add Content” menu has also been updated for greater parity to task creation from the Sample Table Bulk Actions.
Updates to the helper text at the modal to indicate the total number of tasks that will be created.
Administration
The support for Configuration Transfer of Contextual Lists is now available to all systems with a Signals One license.
Integrations & APIs
We have added a new API for querying your current Signals version.
We have added new APIs to support fetching and updating Hierarchical Tables. These APIs allow you to fetch, create, and update content of hierarchical tables.
We have enhanced our API to allow Assets to be added to the Materials Table without requiring a Batch/Lot. The request body will accept the Asset ID where previously it required a Batch ID.
We have added new APIs to bulk update Responsible Person, Amount, and Expiration Date for Containers. This will update the selected field for all Containers included in the request body. Only one of these fields can be bulk updated at a time for all Containers.
The API is asynchronous and kicked off in three steps: Create the Bulk Update Field Job -> Check the Status of the Job -> Get a report of a completed Job as a CSV.
We have added new APIs to bulk return Containers to their Home Locations. This will return all the containers to their Home locations. Only containers with a Home location set will be returned.
The API is asynchronous and kicked off in three steps: Create the Return Home Job -> Check the Status of the Job -> Get a report of a completed Job as a CSV.
We have added new APIs specific to our Synergy Product CROs for attaching files and fetching/updating chemical compliance. These allow for specific APIs to be utilized by CRO users. This enables customers External Actions to read and write for CRO users without exposing details that CROs are restricted from seeing or interacting with.
Beta Features
The following capabilities are in beta and are available for users, administrators and developers on the Signals platform upon request. Please contact your account representative or our support team if you would like access to the following features.
Fundamentals
Ontologies are now supported in Signals. Administrators may connect to most public ontologies available on either the BioPortal or Ontology Lookup Service (OLS) providers.
After connecting to an External Ontology Source, Administrators can subset a specific Ontology into a new type of Attribute List called an Ontology List.
Admins can incorporate Ontology Lists into most Templates within Signals where Attribute Lists are already supported, including Material Definitions, Experiment Templates, Table Templates, Worksheet Templates, Sample Properties, and more
When interacting with a field associated with an Ontology List, users can type-ahead to find a term directly (including matching based on synonym). Alternatively, users can select the magnifying glass icon to browse the hierarchical ontology tree.
You can now split a container into multiple sub-containers with an option to make all aliquot amounts identical. This helps save time and reduce manual entry when preparing multiple identical vials.
When printing Experiments or other objects to PDF, ontology details can be optionally included, which will embed a CSV with ontology metadata, like Preferred Name and IRI.
Tables
The administrative experience for Admin Defined Tables and Variation Tables has been updated to match Hierarchical Tables. This updated design matches that previously released for Hierarchical tables and provides a smoother experience for defining and reordering properties within the table.
Included within the administrative update described above, we have also extended the configuration of Number properties in Admin Defined Tables and Variation Tables. Number properties can be defined with conditions for data entry, ranges can be set and the property set to either not allow an out of range value, or to provide a visual indication when a value does not match.
Materials
Administrators can now configure inherited properties in all material libraries. Data field values can now be passed down (i.e. inherited) from one material to another using internal reference links. Updates to the source data are automatically propagated to any inheriting entity and are kept in sync.