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Signals One™

Science is getting more complex. Simplify it with Signals One™.

Make your innovations a reality with the first unified, cloud-native SaaS R&D solution that simplifies complexity and enhances collaboration across Drug Discovery, Materials, and Food Science.

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An introduction to Signals One

Signals One is an end-to-end R&D workflow solution providing data capture & collaboration, data processing, and data-driven analytics in one unified solution.

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Artificial Intelligence & Machine Learning 

  • Semantic Search – Leverage AI to handle both simple and complex queries, enabling searches in any language for enhanced accessibility and precision.  
  • Summarization Assistant – Generate rapid, efficient summaries while staying securely within the Revvity Signals platform, saving time and boosting productivity.
  • Antibody Developability Dashboard – AI evaluates antibody candidates by predicting structures from sequences, estimating accessible surface areas around potential sequence liabilities, and scoring candidates using adjustable developability metrics, enabling scientists to focus on the most promising designs.
  • AI-ready data - Our solution optimizes data preparation for AI integration, unlocking the full potential of AI's speed and intelligence to bring greater value to your research.

 

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    Design

    Intuitive Structure Drawing & Molecular Design 

    Leverage the only ELN natively integrated with ChemDraw®, the gold-standard chemical drawing and communication software, plus structured, high-quality data and open APIs to integrate AI algorithms for predictive modeling, hypothesis generation, and design optimization. 

    • Draw, edit, and annotate chemical structures with professional-grade ChemDraw tools
    • Access extensive template libraries and reaction schemes seamlessly within your ELN
    • Integrate AI algorithms for predictive modeling and design optimization
    • Hierarchical Editing Language for Macromolecules (HELM) capabilities empower biopolymeric research

    ChemDraw | Revvity Signals Software 

    Make

    Intuitive Data Capture & Collaboration  

    Facilitate collaboration and data management to capture, organize, share, and explore data while planning, performing, and documenting experiments to avoid duplication of work and maximize insights into your wet- and dry-lab workflows. 
     

    • Capture, organize, and customize your data in a modern, user-friendly interface with configurable data connections
    • Collaborate and share insights with colleagues in a permission-managed environment
    • Unified Data Handling - Drag and drop any type of data structured or unstructured for streamlined documentation and analysis
    • Leverage resilient, scalable microservice cloud architecture with frequent SaaS updates and minimal user interruption with our robust REST APIs 

    Signals Notebook | Revvity Signals Software 

    Test

    Advanced Analytics & Data Processing  

    Handle common visualization and analytics use cases with Signals Native Analytics, plus leverage natively integrated Spotfire® for advanced analysis that unites assay development, low- to ultrahigh-throughput production assays, high content screening, and in vivo studies in a single solution.

    • Simple visualization for in vitro curve fitting, in vitro curve fitting and visualization, and group-comparison with Native Analytics
    • Advanced statistical analysis, interactive dashboards, and specialized chemical/biological tools with integrated Spotfire®
    • Central data processing platform that parses instrument files and processes data using automatable calculation templates
    • Unified data ingestion from multiple assay types (HTS, HCS, SPR, in vitro, in vivo) with easy configuration - no IT dependency 

    Signals One Data Processing | Revvity Signals Software

    Decide

    Data-Driven Analytics & Results Management

    This next-generation data management system analyzes scientific results with data-driven analytics capabilities that enable efficient access and analysis of all scientific results collected throughout the R&D lifecycle, providing sub-second query responses across even the largest databases.

    Find and retrieve any test or assay result plus associated compound or biologic sequence information across experiments, projects, and departments.

    • Find and retrieve any test or assay result plus associated compound or biologic sequence information across experiments, projects, and departments
    • Advanced query and data management capabilities with all chemical and biological analytic functionality
    • Transfer relevant data subsets into analytic dashboards without programming, manual data-wrangling, or reformatting
    • Sub-second query responses across massive datasets for instant insights

    Signals One Data Driven Analytics | Revvity Signals Software

    Signals One - Teach Me in 10  

    Novel drug modalities offer great potential but create research and development (R&D) challenges like fragmented workflows and complex data analysis. This video shows how Signals One addresses these issues by integrating data across the entire design-make-test-decide process and enabling cross-disciplinary collaboration.

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    Introducing Signals One at Bio-IT World '25

    Delivering research workflow depth and foster unified breadth of collaboration to accelerate innovation.  This video illustrates a Design-Make-Test-Decide antibody-drug conjugate workflow and highlights three new capabilities coming soon.

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    Compare Products

    Signals Notebook

    Signals One

    Features

    Experiment Execution and Capture
     
     
    Interfaces and integrations
     
     
    Inventory
     
     
    Material management & registration
     
     
    AI - Enhanced User Experience
    —
     
    Structure data handling
    —
     
    Signals Analytics
    —
     
    SAR & Decision Making
    —
     

    Signals One has given Cogent Biosciences the kind of data analytics capabilities that were once the sole domain of big pharma companies with deep pockets and extensive IT departments.

     

    Jennifer Fulton | Cogent Biosciences, Medicinal Chemist (Quote from Make, Test, Decide Nature article)
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    Signals Connect

    Join us for this ongoing Signals Connect community series and learn how you can go beyond and get more out of your data using Signals One. Gain critical insights to accelerate your R&D discoveries.

    Register Now

    • Unlock innovation with Signals One

      AI-enhanced Signals One empowers researchers by providing a cloud-native, unified software platform that spans the entire Design-Make-Test-Decide R&D lifecycle. Collaborate seamlessly across R&D disciplines, adapt to real-time experimental planning and laboratory bench work, and make informed decisions based on comprehensive data analysis to accelerate innovation in bringing products to market.

      Read the Data Sheet

    • Increase the success rate for your drug discovery

      AI-enhanced Signals One gives more scientific quality time to medicinal and synthetic chemists, improving their chances of successfully bringing new therapeutics to market. The only chemistry software solution powered by ChemDraw and Spotfire, Signals One delivers research depth for medicinal chemistry and new drug modalities while fostering unified breadth of collaboration in multidisciplinary workflow.

      Read Now

    • Promoting collaboration between multidisciplinary teams

      AI-enhanced Signals One gives biologists complete control of their workflows across every assay technique, modality, and data type to empower better interaction between multidisciplinary project teams. Whatever the nature of your drug discovery program, Signals One can help you bring your scientific breakthroughs to patients faster.

      Read Now

    • One Solution for Design-Make-Test-Decide

      AI-enhanced Signals One offers top-tier analysis and data visualization throughout the Design-Make-Test-Decide R&D lifecycle. It fosters rapid innovation in the discovery, development, and optimization of biological and chemical modalities, accelerating their journey to market.

      Read Now

    • Unifying Data and AI to Transform Drug Discovery

      The wide deployment of AI is unlocking new efficiencies in research, but its effectiveness depends on workflows and data quality. Signals One enhances research with AI assistance, ontology plug-ins, and automated visualizations, helping researchers reach conclusions faster and advance the best candidates toward clinical development.

      Read Blog

    Upgrade Options:

    Signals Synergy

    Drive innovation through partnering with CROs to achieve more together.

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    Signals DLX

    Pre-built connectors enable rapid integration, unifying your lab ecosystem.

    life cycle connectivity
    Learn More
      Small Molecule Solutions

      Small Molecule Drug Discovery

      Capabilities

      Description

      Benefits

      Compound Synthesis

      Streamlines the process of designing, planning and documenting chemical reactions.

      • Synthesis Workflows
      • Automated Stoichiometric calculations
      • Search prior knowledge
      • Parallel Experiment Management
      • Support for patent applications
      • Integrated chemical intelligence provided by natively integrated ChemDraw® simplifies the designing and documentation process and enhances the overall quality of data management and collaboration enabling researchers to work more efficiently and effectively in their research.
      • HELM capabilities empower new drug modality research of biopolymeric structures

      Compound Analysis

      Researchers can efficiently make test requests, evaluate and interpret experimental data related to chemical compounds.
      • Make assay and test requests in-platform
      • Visualize data using standardized workflows powered by Spotfire®
      • Facilitate collaboration between departments, e.g., medicinal chemist and assay scientist
      • Standardized Statistical Analysis providing cluster analysis and unsupervised machine learning

      Compound Registration

      Enables researchers to efficiently input, manage, and analyze chemical compound data through.

      • Structured Data Entry
      • Centralized management
      • Rapid search and retrieval
      • Materials Management & Registration - Keep track of compounds with continuous barcode inventory and registration support
      • Material Request - Create sharable material libraries to support your workflows
      • Search Inventory for Materials - Search for similar, exact, substructures; know when to order/reorder
      • Access Material Safety Data Sheets - Incorporate and access safety info into your protocols

      Hit Identification

      Empowers researchers to efficiently discover and evaluate potential drug candidates through:

      • High-throughput Screening (HTS) and Virtual Screening
      • Assay development
      • Automated analyses
      • Reduces the time and effort needed to find the one drug candidate within many.
      • Automatic round trip of experimental results from Data Processing capability into Signals® Notebook
      • Graphics driven by Spotfire® enable meaningful visualization of data
      • Workflow templates are set up once, used multiple times

      in vitro analysis

      Developing assays to measure cell activity, processing assay data, visualizing assay results, and analyzing assays using High Content Screening (HCS) and Surface Plasmon Resonance (SPR)
      • In-platform integration throughout the workflow
      • Flexibility to adapt to new assays, instruments, and technology without custom-coding
      • Ability to create workflows that process data quickly, facilitating faster decision-making
      • Native integration with Spotfire® for advanced analytics and visualization

      Lead Optimization

      Self-service analytics and visualization tools to refine promising drug candidates to enhance drug efficacy, safety, and pharmacokinetics properties.

      • Data-drive analysis
      • Standardized workflows
      • In-platform collaboration
      • Facilitates the selection of the most promising compounds for further refinement and development.
      • The only Structure Activity Relationship (SAR) software application with native ChemDraw® integration
      • Dedicated, specialized visualizations for advanced structure-activity relationships, e.g., R-group decomposition, matched-pair analysis, activity cliff, etc.

      Efficacy and Toxicology Studies

      Evaluate biological effects and potential toxicities in animal models through comprehensive data analysis and streamlined reporting workflows

      Predict treatment outcomes and identify potential adverse events at the preclinical stage, thereby reducing risks and enabling the optimization of the drug candidate’s therapeutic profile before clinical trials

      Pharmacokinetics and Pharmacodynamics

      Analyze and model PK/PD profiles to assess how a drug behaves in biological systems

      Gain critical insights empowered by Spotfire® into drug safety, ADME and optimal dosing, helping to optimize clinical trial designs and maximize the likelihood of success in late-stage development.

      Biomarker Discovery

      Identification and validation of biomarkers to measure effects of drug candidates
      • Advanced analytics and visualization empowered by Spotfire® helps reduce the number of variables in complex datasets making data easier to interpret
      • Helps users quickly identify patterns and relationships among variables.
      Large Molecule Solutions

      Biologics Discovery

      Capabilities

      Description

      Benefits

      Biologics Registration

      Create biological modality libraries easily to track and connect relevant datasets

      • Integration with Signals® Notebook to search and synchronize experimental records and materials
      • Linking biologic registration data (e.g., antibody sequences, cell lines) with assay results for better traceability

      Centralizes all drug modality material assets, improving data accessibility and reducing duplication, thereby enhancing efficiency in research workflows

      Assays

      Build, define and manage biological assay workflows

      • Creating and standardizing protocols for cell-based or biochemical assays
      • Automating data entry and reporting for high-throughput screening (HTS) workflows

      Streamlines assay processes, enhances reproducibility, and reduces time-to-data for decision-making, leading to more efficient experimental outcomes

      Results Analysis

      Access to key datasets quickly within experimental, project, and program contexts

      • Automated aggregation of sequence intelligent datasets to identify targets of interest
      • Visualization tools like heatmaps and clustering for trend identification in screening campaigns
      • Machine learning models to predict assay outcomes and flag anomalous data points

      Accelerates identification of key patterns and trends, enabling faster hypothesis validation and data-driven decisions, ultimately advancing research objectives

      Hit Identification

      Empowers researchers to efficiently discover and evaluate potential drug candidates through:

      • High-throughput Screening (HTS) and Virtual Screening
      • Assay development
      • Automated analyses
      • Reduces the time and resources needed for early-stage drug discovery while improving the quality of lead candidates, thereby increasing the likelihood of successful outcomes
      • Integrating drug screening data from various sources for centralized evaluation
      • Interactive dashboards to compare hits across multiple assay conditions

      in vitro analysis

      Developing assays to measure cell activity, processing assay data, visualizing assay results, and analyzing assays using High Content Screening (HCS) and Surface Plasmon Resonance (SPR)
      • In-platform integration throughout the workflow
      • Flexibility to adapt to new assays, instruments, and technology without custom-coding
      • Ability to create workflows that process data quickly, facilitating faster decision-making
      • Native integration with Spotfire® for advanced analytics and visualization

      Lead Optimization

      Optimize lead compounds by integrating multi-parameter datasets, predictive modeling, and workflow automation to refine drug candidates

      • Enabling BioSAR (Sequence-Activity Relationship) analysis to prioritize hit candidates
      • Facilitates the selection of the most promising biologics for further development.

      Pharmacokinetics and Pharmacodynamics

      Analyze and model PK/PD profiles to assess how a drug behaves in biological systems, enabling dosing strategies

      Mitigate late-stage failures by predicting human responses early in the development pipeline, saving time and resources

      Efficacy and Toxicology Studies

      Evaluate biological effects and potential toxicities in animal models through comprehensive data analysis and streamlined reporting workflows

      Predict treatment outcomes and identify potential adverse events at the preclinical stage, thereby reducing risks and enabling the optimization of the drug candidate’s therapeutic profile before clinical trials
      Product Formulation Solutions

      Formulation Development

      Capabilities

      Description

      Benefits

      R&D Workflow Management

      Centralized and structured data capturing and organization help teams plan, track, and optimize R&D activities throughout the entire R&D lifecycle.

      Ensures structured workflows, version control, and transparency, ultimately accelerating innovation and improving project outcomes.

      Ingredient Information Management

      Comprehensive, configurable, and searchable material information library:

      • Centralized Ingredient Database
      • Supplier Data Integration
      • Search & Reporting Tools

      Reduces errors by centralizing and standardizing ingredient data across teams and systems to facilitate product development.

      Inventory and Sample Management

      Access to key datasets quickly within experimental, project, and process contexts

      • Safety Data Management
      • Supplier Data Integration
      • Risk & Hazard Assessment

      Optimizes chemical and biological inventory control, tracks samples accurately, reduces waste, and enhances safety and operational efficiency.

      Formulation Information Organization

      Empowers researchers to efficiently discover and evaluate formulation candidates through:

      • Approval Workflows: Formulation submission, review, and approval
      • Formulation Templates & Guidelines
      • Faster Time-to-Market:
      • Early Regulatory and safety risk identification
      • Improved Data Accuracy: Ensures consistency and reduces errors 

      Advanced Data Analytics and Visualization
      • Interactive, Real-time, customizable Dashboards
      • Data Integration from multiple sources
      • Self-Service Analytics
      • Advanced Charting Options
      • Collaboration Tools 
      • Faster Decision-Making
      • Improved Accuracy
      • Better Forecasting
      • Enhanced Visibility
      • Increased Efficiency
      • Cross-Functional Alignment
      • Scalability
      • Transforms raw data into strategic insights

      Predictive Modeling and Formulation Optimization

      Leverage machine learning, and statistical analysis to enhance formulations, predict outcomes, balance objectives, and ensure regulatory compliance and performance efficiency.

      • Multi-Objective Optimization
      • Constraint Management
      • Iterative Learning: Continuously improves model accuracy by incorporating new data and test results.
      • Scenario Analysis & Simulation: Tests different ingredient scenarios to forecast outcomes before actual testing.

      Streamline product development, enhance performance, and reduce costs. Here are the key benefits:

      • Faster Product Development & Enhanced Performance:
      • Cost Efficiency: Helps identify cost-effective ingredient alternatives, minimizing waste and maximizing resources through intelligent, data-driven decisions.
      • Risk Reduction: Reduces trial-and-error, enhances formulation accuracy, and ensures compliance, improving product success rates and minimizing costly failures.

      Safety and Regulatory Risk Assessment
      • Risk Identification & Evaluation
      • Automated Risk Assessment
      • Documentation & Audit Management: Organizes regulatory documentation, facilitates audits, and ensures proper record-keeping for compliance.
      • Reporting & Dashboard Tools
      • Collaboration Features
      • Reduces Risk Exposure: Identifies potential regulatory risks early, allowing companies to proactively address and mitigate them before they become costly issues.
      • Improves Efficiency: Automates manual processes for risk evaluation, documentation management, and reporting, saving time and resources.
      • Enhances Decision-Making
      • Streamlines Audits

      R&D Project Management
      • Project Planning & Scheduling
      • Collaboration Tools
      • Task & Milestone Tracking
      • Reporting & Analytics
      • Compliance Tracking
      • Integration with Other Systems
      • Enables efficient project planning, scheduling, resource allocation, collaboration, risk management, compliance tracking, and real-time reporting, streamlining research workflows and ensuring timely, budget-compliant project delivery.

       

       

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      SignalsNotebook

      The premier cloud-based electronic lab notebook for biologists and chemists to collaborate, capture, organize, share, and explore data.

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      Signals Synergy Icon

      SignalsSynergy

      Enhancing collaboration and information exchange between Sponsors and CROs.

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      Signals DLX

      Streamline workflows with Signals DLX powered by Scitara. Enable rapid integration, unifying lab ecosystems for improved productivity.

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      Lead Discovery Premium

      Analyze and visualize chemical structure & biological sequence SAR data. Compare and score segment leads based on multi-parametric optimization.

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      Related Events & Webinars

      Resources

      Signals One is ideally suited to handle research use cases involving earlier stage in-vitro assays, later stage in-vitro assays, cell line optimization, biologics process optimization, in vitro DMPK assays, animal pharmacokinetic studies, stage animal efficacy and safety studies.

      More Resources

      Frequently Asked Questions (FAQs)

      In what ways does the Signals One support the development of new drug modalities?

      Signals One is designed to handle the complexities associated with developing new drug modalities, such as protein degraders, RNA therapeutics, antibody-drug conjugates (ADCs), next-generation peptides, and gene therapies. It facilitates laboratory workflows, allowing the capture and analysis of diverse data types required for these advanced therapeutics. By providing tools for assay development, hit identification, and lead optimization, Signals One accelerates the drug discovery process for these novel therapeutics.

      How does Signals One ensure data security and regulatory compliance?

      Signals One implements 24/7 global security monitoring, alerting, and escalation by the Revvity Signals Software Security Operations Center. It supports both multi-tenant and private-cloud deployments and meets standard IT requirements for automatic updates and cloud security controls. The platform also ensures data is findable, accessible, interoperable, and reproducible (FAIR), aiding in data integrity and regulatory compliance.

      What benefits does the Signals One offer to scientists?

      Benefits include:

      • Streamlined collaboration and data sharing across R&D disciplines.
      • Accelerates innovation.
      • Simplified screening and optimization processes.
      • Reduced new product development timelines.
      • Better decision-making with easier data sharing.

      What makes the Signals One unique compared to other solutions?

      Unlike siloed point solutions, Signals One offers a fully integrated platform that encapsulates trusted products, avoiding the complexities and inefficiencies of a piecemeal, application-centric ecosystem. It is the first solution released under the new Revvity Signals Software brand, emphasizing seamless scientific collaboration and data sharing.

      Proud Partnerships